Abstract: To solve the high water cut or watered out which has occurred in horizontal wells completed with screen in the late development stage,the completion with flow control screen for horizontal wells has been developed.Firstly,a 3D model was set up using mathematical simulation method to obtain the flowing characteristics of fluid in the flow control screen,and then the relationships between viscosity,flow rate and pressure difference were determined by lab test,and the corresponding mathematical model was set up,finally basic properties of the screen pipe and flow control ability were tested by using screen performance evaluation device.The technique has been used on 12 wells in Shengli Oilfield,which had verified the results of mathematical simulation and laboratory test,and proved the performance of flow control screen met the demand of field application,pressure control structure could effectively control and block fluid flow in horizontal wells,meeting design requirement.By decreasing water cut of horizontal wells,the technique could extend the working life of the oil wells.