Abstract: To improve the effect of sand control of mesh type screen,the way to select sand blocking layer (fine mesh) was studied.Core sand flow test device with multi-point pressure measurement was established,and the effect of layer number,arrangement angle,setting order,sand heterogeneity and fine silt (particle size less than 0.05 mm) mass fraction on sand blocking accuracy and sand control results were studied systematically.The results showed that,when the fine mesh sand control precision was ω ≤ 0.8d50 in homogeneous sand and ω≤ 0.65d50 in heterogeneous sand,the sand content in produced liquid was less than the industrial standard of 0.03%.The evaluation and optimization of technical parameters affecting sand control accuracy of the mesh type screen provided theoretical basis for improving sand control of mesh type screen.