Abstract: A large leakage horizontal well in a fracture-vuggy carbonate reservoir in the eastern part of South China Sea has the problem of seeing water early and getting water quickly. Under the influence of the bottom water communicated by the seam hole network, the traditional mechanical and chemical water control methods are unable to solve the water problem of wells in this reservoir. To this end, a particle throughput water control technology that can effectively solve the water problem of such wells is proposed, the principle of which is to utilize the leakage of the carbonate formation slit-hole network to "swallow" a large number of low-density particles (with a density of 1.05 g/cm³), which are stable in physicochemical properties with the main body of resins, to improve the non-homogeneity of the formation; some of the particles in the network will be gradually "swallowed" again after the commissioning of the network. After production, some of the particles in the slit hole network are gradually "spit back" into the annulus of the wellbore and the near-well zone to improve the water flushing problem in the annulus and the near-well zone. The results of indoor particle huff and puff simulation show that Particles can enter the experimental fracture model when the flow rate is greater than 0.0033 m/s, and particles can move in the experimental fracture model when the flow rate is greater than 0.009 m/s. The particle throughput condition is easily realized in the field. The technology was applied to 3 new wells and 1 old well in a fracture-vuggy reservoir, and the water content reduction was 5-10 percent point compared with the adjacent wells or the wells before the measures, and the cumulative oil increase was 3×10⁴ m³ to 8×10⁴ m³, which showed obvious water control and oil increase effects. The proposed particle huff and puff technology provides a new solution to the water discharge problem of large leakage horizontal wells in fracture-vuggy carbonate reservoirs.